February 25, 2022

Adjuvant darolutamide prolongs survival in metastatic, hormone-sensitive prostate cancer

Researchers from a phase 3 clinical trial report that addition of the androgen-receptor inhibitor darolutamide to androgen-deprivation therapy and chemotherapy significantly prolongs the survival of men with metastatic, hormone-sensitive prostate cancer. The findings appeared on February 18, 2022 in the NEJM/New England Journal of Medicine. As background, the authors noted that darolutamide therapy has previously been associated with increased overall survival […]

admin Health 0 1 min read
February 10, 2022

Largest genetic study of migraine to date reveals new genetic risk factors

An international consortium of leading migraine scientists identified more than 120 regions of the genome that are connected to risk of migraine. The groundbreaking study helps researchers better understand the biological basis of migraine and its subtypes and could speed up the search for new treatment of the condition, which affects over a billion individuals worldwide. In the largest genome […]

admin Health 0 3 min read
February 5, 2022

European Commission approves Vaxneuvance (pneumococcal 15-valent conjugate vaccine) for individuals 18 years of age and older – Merck Inc

Merck Inc., announced that the European Commission (EC) has approved Vaxneuvance (Pneumococcal 15-valent Conjugate Vaccine) for active immunization for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae in individuals 18 years of age and older. The approval allows marketing of Vaxneuvance in all 27 European Union (EU) Member States plus Iceland, Norway and Lichtenstein. The use of […]

admin Health 0 2 min read
January 28, 2022

Nanoparticle-formulated drug combination is effective in medulloblastoma, a pediatric brain tumor

UNC Lineberger Comprehensive Cancer Center researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma. The research team believes this laboratory success could be translated into a less toxic treatment for medulloblastoma, the most common malignant pediatric brain tumor. Advances such as this […]

admin Health 0 3 min read
December 29, 2021

New resistance-busting antibiotic combination could extend the use of ‘last-resort’ antibiotics

Scientists have discovered a new potential treatment that has the ability to reverse antibiotic resistance in bacteria that cause conditions such as sepsis, pneumonia, and urinary tract infections. Carbapenems, such as meropenem, are a group of vital often ‘last-resort’ antibiotics used to treat serious, multi-drug resistant infections when other antibiotics, such as penicillin, have failed. But some bacteria have found […]

admin Health 0 4 min read
December 28, 2021

Identifying rare disease-associated genetic variants in patients with severe schizophrenia

New research published in the Proceedings of the National Academy of Sciences shows that examining genetic mutations in individuals with severe schizophrenia can improve the ability to detect disease-associated rare genetic variants. The research was conducted at Columbia University Irving Medical Center and led by Dr. Anthony Zoghbi, now assistant professor of molecular and human genetics and psychiatry and behavioral sciences at […]

admin Health 0 2 min read
December 21, 2021

FDA approves Tecartus for B-cell precursor acute lymphoblastic leukemia – Kite

Kite announced the FDA has granted approval for Tecartus (brexucabtagene autoleucel) for the treatment of adult patients (18 years and older) with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). Following FDA Breakthrough Therapy Designation and a priority review, Tecartus is the first and only chimeric antigen receptor (CAR) T-cell therapy approved for adults (18 years and older) with […]

admin Health 0 48 sec read
December 16, 2021

Trigger found for harmful inflammation in lupus, macular degeneration

Researchers at the University of Virginia School of Medicine have made a discovery linking lupus, a potentially debilitating autoimmune disorder, and macular degeneration, a leading cause of blindness. The two diseases share a common contributor to harmful inflammation, the scientists found. The insights could let researchers develop new treatments for those diseases and other conditions driven by the newly discovered […]

admin Health 0 2 min read
December 11, 2021

Breakthrough in understanding motor neuron disease

Researchers at Trinity College Dublin have made a major discovery in understanding motor neuron disease (MND). The research team has found that MND has 4 distinct patterns of changes in electrical signals that can be identified using EEG (electroencephalography). This breakthrough will be extremely valuable in identifying patients for clinical trials and will assist in finding new treatments for this […]

admin Health 0 2 min read
December 8, 2021

How the superbug Pseudomonas aeruginosa reacts to antibiotics

The bacterium Pseudomonas aeruginosa is resistant to all antibiotics on the market. Therefore, there is a great need for new therapeutic approaches. In order to find them, it helps to understand how the germ reacts to active substances. Researchers at Ruhr-Universität Bochum (RUB) have studied how different drugs affect the difficult-to-treat bacterium Pseudomonas aeruginosa. According to the World Health Organisation, new […]

admin Health 0 2 min read

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