Breaking down cancer’s defences

Bacteria generally have a bad reputation, as people first think of certain strains that can cause serious illnesses like pneumonia or meningitis. However, there are many helpful bacteria, known as probiotics, that assist the body in different ways. University of Cincinnati researchers have now engineered a probiotic designed to target and break down cancer cell defenses, giving therapies an easier […]

Kidney cancer: children in the UK and Ireland diagnosed late

Children with kidney cancers in the UK and Ireland are diagnosed with larger and more advanced tumours than in other Western European countries, according to research presented at the National Cancer Research Institute (NCRI) Festival in the UK. As a result, a leading childhood cancer expert has called for all staff providing primary healthcare for children in the UK’s National […]

Lung cancer screening for survivors of head and neck cancer

Head and neck cancer survivors with long smoking histories had a 2.5-fold greater risk of developing lung cancer than those without prior head and neck cancer, according to a secondary analysis of the National Lung Screening Trial (NLST) data.1 The landmark NLST randomized more than 50,000 participants at high risk for lung cancer in a 1:1 ratio to either low-dose […]

Using artificial intelligence for early detection and treatment of illnesses

Artificial intelligence (AI) will fundamentally change medicine and healthcare: Diagnostic patient data, e.g. from ECG, EEG or X-ray images, can be analyzed with the help of machine learning, so that diseases can be detected at a very early stage based on subtle changes. However, implanting AI within the human body is still a major technical challenge. TU Dresden scientists at […]

Vitamin C essential for immune cell function

Investigations carried out at the La Jolla institute for Immunology (LJI) Show that the combination of vitamin C and TET proteins are essential for the proper function of regulatory T-cells (Tregs). Regulatory T cells help control inflammation and autoimmunity in the body. Tregs are so important, in fact, that scientists are working to generate stable induced Tregs (iTregs) in vitro […]

Parkinson’s disease: How lysosomes become a hub for the propagation of the pathology

Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential to develop efficient treatments against these incurable diseases. However, our knowledge about the basic molecular mechanisms underlying the pathogenesis of neurodegenerative diseases is still lacking. A team of […]