Researchers report that patients with knee osteoarthritis have achieved significant short-term pain relief with ultrasound-guided genicular nerve blocks (GNB), locally injected anesthetics that block nerves around the knee joint. The findings were published on Nov. 12, 2022 in Arthritis & Rheumatology. “This study demonstrates that genicular nerve block is an effective short-term therapy for pain management in people with knee […]
Aging is universal. Both osteoporosis and the bone fractures that occur as a result of osteoporosis become more likely with age. Current clinical guidelines do not recommend bed rest during treatment for osteoporotic vertebral fractures—spinal fractures that occur in bones that has been weakened by osteoporosis—because there has not been enough evidence to make conclusive recommendations. However, a recent study […]
Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoporosis occurs when osteoclasts dominate without adequate bone formation to compensate. In new research published in the Journal of Bone and Mineral Research, elevated blood levels of a certain chemokine, or small signaling protein, that promotes osteoclast formation were linked with a higher risk […]
The American College of Rheumatology (ACR) released a summary of its new treatment guideline for Vaccinations in Patients with Rheumatic and Musculoskeletal Diseases (RMDs). The effectiveness and safety of vaccines may differ in rheumatology patients as compared to the general population. The guideline summary provides recommendations on topics such as broadened indications for some vaccines in patients on immunosuppressants, medication management at […]
Thousands of people in England and Wales with severe osteoporosis who are at high risk of fracture are set to benefit from a new treatment – romosozumab (Evenity™, UCB) – after NICE recommended it for people after menopause in final draft guidance published on 1st April by NICE. Over 20,000 people could be eligible for the treatment according to the […]
Pfizer and OPKO Health announced that the European Commission has granted marketing authorization for the next-generation long-acting recombinant human growth hormone Ngenla (somatrogon), a once-weekly injection to treat children and adolescents from 3 years of age with growth disturbance due to insufficient secretion of growth hormone. Ngenla provides pediatric patients, their caregivers and healthcare providers with a new treatment option […]
The menopause transition is associated with several health issues. The incidence of both sleep apnea and joint pain, for example, are higher in postmenopausal women. A new study aimed to investigate the association between various physical and psychological symptoms common during the menopause transition with sleep apnea. Study results are published online today in Menopause, the journal of The North American […]
Although fractures normally heal, bone will not regenerate under several circumstances. When bone does not regenerate, major clinical problems could result, including amputation. To enhance the regeneration of bone, the Food and Drug Administration (FDA) approved recombinant human bone morphogenetic protein-2, or BMP-2. However, it is expensive and only moderately effective. It also produces side effects ? some severe. Researchers […]
Multiple sclerosis (MS), a progressive disease that affects 2.8 million people worldwide and for which there is no definitive cure, is likely caused by infection with the Epstein-Barr virus (EBV), according to a study led by Harvard T.H. Chan School of Public Health researchers. Their findings will be published online in Science. “The hypothesis that EBV causes MS has been investigated […]
Roche announced data from across its growing neuromuscular portfolio at the World Muscle Society (WMS) Virtual Congress 20 – 24 September 2021. The presentations included additional results from the RAINBOWFISH study, evaluating the efficacy and safety of Evrysdi (risdiplam) in babies with pre-symptomatic spinal muscular atrophy (SMA) from birth to six weeks of age and data. At WMS 2021, data […]
Recent Comments