A new class of immunotherapy shows promising results for fighting the most aggressive form of skin cancer. The study, published today in Nature Communications by researchers from King’s College London and Guy’s and St Thomas’ NHS Foundation Trust, investigates whether a novel antibody can target and treat melanomas. The results show that the antibody activates the immune response to fight cancer and […]
CAR-T cell therapy has been shown to be highly effective in treating some cancers. However, responses to this relatively new form of immunotherapy can vary, making it difficult for patients and doctors to predict cancer outcomes. Scientists have been puzzled by the range of responses. Now a new study by the German Cancer Research Centre (KDFZ), in collaboration with researchers […]
Mount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the blood cancer multiple myeloma who try an immunotherapy known as CAR-T only to find their cancer coming back afterwards. CAR-T, short for chimeric antigen receptor T-cell therapy, enlists immune cells called T cells to fight multiple myeloma by altering them in […]
Researchers reported a 20 percent advantage in the two-year overall survival rate for subjects with advanced melanoma and a mutation in the BRAF gene, specifically a BRAF V600 mutation, who were initially treated with immunotherapy (72 percent survival rate) compared with subjects initially treated with targeted therapies (52 percent survival rate). The findings from the DREAMseq trial were published on September 28, 2022 in […]
A University of Cincinnati study found administering an immunotherapy drug before surgery for oral cavity cancer did not lead to increased rates of complications during and after surgery. The findings were published Aug. 25 in the journal JAMA Otolaryngology — Head & Neck Surgery. Alice Tang, MD, first author on the study, said the research built upon previous findings led by […]
UBC researchers demonstrated in 2019 that pre-schoolers can safely overcome peanut allergies with a treatment called oral immunotherapy. Now they have evidence that the earlier pre-schoolers start this treatment, the better. This real-world study focused on infants younger than 12 months old and reveals that not only is oral immunotherapy effective against peanut allergies, it’s even safer for this age […]
A new approach from Penn Medicine researchers could cut the time it takes to alter patients’ immune cells for infusion back into the body to find and attack cancer. The cell manufacturing process for this type of immunotherapy that was pioneered at Penn — CAR T cell therapy — typically takes nine to 14 days. In a pre-clinical study published […]
University of Illinois Chicago researchers have developed a compound that may one day offer hope for pancreatic cancer treatment. A pre-clinical study of the experimental compound shows that it more than doubles the average survival time for mice with pancreatic cancer and that survival time was extended further when combined with immunotherapy. Led by Ajay Rana, professor of surgery at the UIC […]
In a new study by Yale Cancer Center, researchers show stem-like T cells within certain lymph nodes could be natural cancer fighters. Targeting these T cells, which are a type of white blood cells, with immunotherapy drugs could increase the number of cancer patients that respond to treatment. The findings were reported online today in the journal Science Immunology. “Therapies that […]
Researchers at the Francis Crick Institute have identified a protein that helps tumours evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target for future cancer treatments. A crucial part of the immune system’s response to cancer is a group of white blood cells, called CD8+ […]
Recent Comments