New tool to create hearing cells lost in aging

Hearing loss due to aging, noise and certain cancer therapy drugs and antibiotics has been irreversible because scientists have not been able to reprogram existing cells to develop into the outer and inner ear sensory cells — essential for hearing — once they die. But Northwestern Medicine scientists have discovered a single master gene that programs ear hair cells into […]

Third dose of COVID-19 vaccine does not appear to increase severe adverse events

Investigators report that even though there was some increase in cases of low-severity adverse events after third-dose vaccination against SARS-CoV-2 infection with mRNA vaccines, such third-dose vaccination did not significantly increase severe adverse events. The findings appeared on April 14, 2022 in JAMA Network Open. As background the authors said. “Recent reports on waning of COVID-19 vaccine–induced immunity have led […]

Researcher finds over-the-counter meds a ‘needle in the haystack’ of the larger pain pill epidemic

Drug misuse is not exclusive to the opioid epidemic, according to a recent West Virginia Universitystudy. Every year, about 50,000 people in the United States are admitted to the emergency room due to misuse of a common over-the-counter pain medication – acetaminophen. With that in mind, Mark Garofoli, director of experiential learning at the WVU School of Pharmacy, spearheaded research that revealed that the public’s […]

Recreational marijuana access reduces demand for prescription drugs

Legalization of recreational marijuana reduces demand for costly prescription drugs through state Medicaid programs, according to an analysis by a Cornell researcher and a collaborator. When states legalize marijuana, the volume of prescriptions within the drug classes that align with the medical indications for pain, depression, anxiety, sleep, psychosis and seizures significantly decline, the researchers found. Shyam Raman, a doctoral […]

Sodium valproate – the risks for pregnant women

A recent newspaper article drew attention to the increased risks of birth defects in children of mothers who have taken sodium valproate during pregnancy. IMI spoke to experienced mental health pharmacists, Yogita Dawda and Anshu Rayan to find out more about the risks and what can be done to raise awareness and minimise risks. As deputy chief pharmacist at Central […]

Conventional vaccine messages miss the mark

Promotional campaigns designed to increase vaccine uptake are often ineffective, according to a new study in eight European countries. Some initiatives which highlight the benefits of immunisation may even be counterproductive, say scientists. Researchers at the Technical University of Munich worked with colleagues at the University of Trento and the London School of Economics and Political Science to test the […]

Just over half of Michigan pharmacies offer overdose-fighting naloxone without prescription

Despite the ability of any Michigan pharmacy to dispense medication to combat opioid overdose without writing prescriptions, slightly more than half of pharmacies in the state offer the drug in such a way. The standing order for naloxone, commonly known as Narcan, was passed by the Michigan legislature in 2016. This allows any pharmacist to dispense the overdose reversal drug without […]

Boost for global access to diabetes treatments

Two established diabetes medicines have been given the green light for use outside the EU – even when stored at higher temperatures – under the EU Medicines for All (EU-M4All) scheme. This procedure allows the European Medicines Agency (EMA) to assess the quality, safety and efficacy of medicines that address an unmet medical need or a public health concern outside […]

EU experts cautious on fourth dose of COVID-19

It is ‘too early’ to consider using a fourth dose of mRNA COVID-19 vaccines in the general population, according to the European Medicines Agency (EMA) and the European Centre for Disease Prevention & Control (ECDC). However, experts from both agencies agreed that a fourth dose – or second booster shot – can be given to adults 80 years of age. […]

Gastrointestinal issues linked with anxiety, social withdrawal for kids with autism

Children with autism spectrum disorder tend to experience gastrointestinal issues, such as constipation and stomach pain, at a higher rate than their neurotypical peers. Some also experience other internalizing symptoms at the same time, including stress, anxiety, depression and social withdrawal. Until now, no studies have examined the causal relationship between gastrointestinal symptoms and internalizing symptoms. A new study at […]