Severe infections during pregnancy associated with complications around childbirth

Researchers recommend increased prenatal surveillance for patients with sepsis and other serious infections University of California – San Francisco Individuals who are hospitalized during pregnancy due to sepsis have higher odds of complications surrounding childbirth, according to a study led by researchers at UC San Francisco. The study found that pregnancies complicated by sepsis were associated with an increased risk […]

FDA approves Trudhesa nasal spray for the treatment of acute migraine – Impel Neuropharma

Impel NeuroPharma, Inc. announced that the FDA approved Trudhesa (dihydroergotamine mesylate) nasal spray (0.725 mg per spray) for the acute treatment of migraine with or without aura in adults. Trudhesa was previously known as INP 104. Using Impel’s proprietary Precision Olfactory Delivery (POD ) technology, Trudhesa gently delivers dihydroergotamine mesylate (DHE)—a proven, well-established therapeutic—quickly to the bloodstream through the vascular-rich […]

Moderna announces submission of initial data to the FDA for mRNA-1273 at the 50 µg dose level

Moderna, Inc., announced it has initiated its submission to the FDA for the evaluation of a booster dose of the Moderna COVID-19 vaccine (mRNA-1273) at the 50 µg dose level. The Company expects to submit data to the European Medicines Agency (EMA) and other regulatory authorities around the world in the coming days. </p. The Phase II study of mRNA-1273 […]

Can gastrointestinal bleeding after heart attack be predicted?

Knowing which patients are at higher risk of bleeding complications following a heart attack can help health professionals to take preventative measures. Now researchers at Karolinska have published a list of eight key primary factors that increase the risk of gastrointestinal bleeding. While some of these had previously been identified, the study used machine learning techniques to pinpoint additional predictors, […]

Making CAR-T therapy most effective in leukaemia patients

Too many “exhausted” T cells left in the wake of aggressive chemotherapy regimens for patients with advanced chronic lymphocytic leukaemia (CLL) make it more challenging for chimeric antigen receptor (CAR) T cell therapy to do its job. Now, a new study from researchers at the University of Pennsylvania shows how to overcome this type of resistance and reinvigorate these T […]

Exercise maintains heart rhythm in patients with atrial fibrillation

A six-month exercise programme helps maintain normal heart rhythm and reduces the severity of symptoms in patients with atrial fibrillation, according to a study by researchers at the University of Adelaide, Australia. Atrial fibrillation (AF) is a heart rhythm disorder that makes the heart beat rapidly and irregularly. The most common symptoms are palpitations, shortness of breath, light headedness, and fatigue, […]