The FDA has approved Qulipta (atogepant tablets), from AbbVie, for the preventive treatment of episodic migraine in adults. The approval of Qulipta was based on findings from the Phase III ADVANCE study, a Phase II/III efficacy, safety, and tolerability study, and a Phase III long-term safety study. In the pivotal Phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group ADVANCE trial, 910 […]
BioDelivery Sciences International, Inc. a growing specialty pharmaceutical company dedicated to patients living with chronic conditions, announced that it has completed the acquisition of U.S. and Canadian rights to Elyxyb (celecoxib oral solution) from Dr. Reddy’s Laboratories Limited. Elyxyb is the first and only FDA-approved ready-to-use oral solution for the acute treatment of migraine, with or without aura, in adults. […]
Scientists have long wondered why almost all animals sleep, despite the disadvantages to survival of being unconscious. Now, researchers led by a team from the University of Tsukuba have found new evidence of brain refreshing that takes place during a specific phase of sleep: rapid eye movement (REM) sleep, which is when you tend to dream a lot. Previous studies […]
Impel NeuroPharma, Inc. announced that the FDA approved Trudhesa (dihydroergotamine mesylate) nasal spray (0.725 mg per spray) for the acute treatment of migraine with or without aura in adults. Trudhesa was previously known as INP 104. Using Impel’s proprietary Precision Olfactory Delivery (POD ) technology, Trudhesa gently delivers dihydroergotamine mesylate (DHE)—a proven, well-established therapeutic—quickly to the bloodstream through the vascular-rich […]
University of California San Francisco Technology could lead to more natural communication for people who have suffered speech loss Researchers at UC San Francisco have successfully developed a “speech neuroprosthesis” that has enabled a man with severe paralysis to communicate in sentences, translating signals from his brain to the vocal tract directly into words that appear as text on a […]
Researchers report in a newly published study of vasovagal syncope in younger, otherwise healthy patients, that treatment with oral midodrine significantly decreases fainting spells. Vasovagal syncope is the most common cause of fainting, and it happens when the blood vessels open too wide and/or the heartbeat slows. The findings were published on August 3, 2021 in Annals of Internal Medicine. “Recurrent […]
It’s so commonplace we barely give it a second thought, but human brains seem hardwired to see human faces where there are none — in objects as varied as the moon, toys, plastic bottles, tree trunks and vacuum cleaners. Some have even seen an imagined Jesus in cheese on toast. Until now scientists haven’t understood exactly what the brain is […]
“Migraine is one of the most common headache disorders, but only about half the people taking medication for it get real relief,” said study author Rohit Bhatia, M.D., D.M., D.N.B., of the All India Institute of Medical Sciences in New Delhi, India, and a member of the American Academy of Neurology. “The good news is that practicing something as simple […]
Université de Genève One person in 2000 suffers from a microdeletion of chromosome 22 that can lead to the development of psychotic disorders, such as schizophrenia, in adolescence. In addition to symptoms such as hallucinations or delusions, psychotic disorders also comes with a progressive decline in intelligence quotient (IQ). If current drug treatments are successful in containing psychotic symptoms, nothing […]
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