How do our eyes stay focused on what we reach for? Researchers uncover how our gaze is “anchored” in the brain

Keeping our eyes focused on what we reach for, whether it be an item at the grocery store or a ground ball on the baseball field, may appear seamless, but, in fact, is due to a complex neurological process involving intricate timing and coordination. In a newly published study in the journal Nature, a team of researchers sheds additional light on […]

Pharmacy researchers receive patent for chemical probe

Many brain diseases and disorders lead to neuroinflammation, a swelling of brain tissue that is increasingly recognized as one of the telltale signs and disease progression factors of Alzheimer’s and Parkinson’s disease. Neuroinflammation can limit blood flow to areas in the brain, which can lead to the inhibition of the body’s natural disease fighting mechanisms. Traumatic brain injuries also cause […]

Researchers map human sensory neurons, pursue chronic pain cure

An investigation into how human nerve cells differ from animal cells has provided researchers from The University of Texas at Dallas’ Center for Advanced Pain Studies (CAPS) with important clues in the pursuit of more effective treatments for chronic pain. Dr. Ted Price BS’97, Ashbel Smith Professor of neuroscience in the School of Behavioral and Brain Sciences (BBS) and CAPS […]

Team uses MRI to image epigenetics in the brain

A multidisciplinary team at the University of Illinois Urbana-Champaign has devised a new approach to 3D imaging that captures DNA methylation, a key epigenetic change associated with learning in the brain. The scientists say their proof-of-concept study in pigs will easily translate to humans, as the new method relies on standard MRI technology and biological markers already in use in […]

Largest genetic study of migraine to date reveals new genetic risk factors

An international consortium of leading migraine scientists identified more than 120 regions of the genome that are connected to risk of migraine. The groundbreaking study helps researchers better understand the biological basis of migraine and its subtypes and could speed up the search for new treatment of the condition, which affects over a billion individuals worldwide. In the largest genome […]

Nanoparticle-formulated drug combination is effective in medulloblastoma, a pediatric brain tumor

UNC Lineberger Comprehensive Cancer Center researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma. The research team believes this laboratory success could be translated into a less toxic treatment for medulloblastoma, the most common malignant pediatric brain tumor. Advances such as this […]

Roche presents new data for Evrysdi at World Muscle Society (WMS) 2021 highlighting new advances for people living with rare neuromuscular disorders

Roche announced data from across its growing neuromuscular portfolio at the World Muscle Society (WMS) Virtual Congress 20 – 24 September 2021. The presentations included additional results from the RAINBOWFISH study, evaluating the efficacy and safety of Evrysdi (risdiplam) in babies with pre-symptomatic spinal muscular atrophy (SMA) from birth to six weeks of age and data. At WMS 2021, data […]

‘Surprisingly simple’ arithmetic of smell

Adding and subtracting certain neurons tells researchers whether or not a locust can smell an odor. Smell it inside or outside; summer or winter; in a coffee shop with a scone; in a pizza parlor with pepperoni — even at a pizza parlor with a scone! — coffee smells like coffee. Why don’t other smells or different environmental factors “get […]

How the brain’s blue spot helps us focus our attention

The neurotransmitter noradrenaline regulates our brain’s sensitivity to relevant information. How can we shift from a state of inattentiveness to one of highest attention? The locus coeruleus, literally the “blue spot,” is a tiny cluster of cells at the base of the brain. As the main source of the neurotransmitter noradrenaline, it helps us control our attentional focus. Synthesizing evidence […]