Moderna, Inc., announced it has initiated its submission to the FDA for the evaluation of a booster dose of the Moderna COVID-19 vaccine (mRNA-1273) at the 50 µg dose level. The Company expects to submit data to the European Medicines Agency (EMA) and other regulatory authorities around the world in the coming days. </p. The Phase II study of mRNA-1273 […]
Pfizer Inc. announced that the FDA has approved Ticovac (tick-borne encephalitis (TBE) vaccine) for active immunization to prevent TBE in individuals 1 year of age and older. Ticovac is the only FDA-approved vaccine to help protect U.S. adults and children against the TBE virus when visiting or living in TBE endemic areas. Following today’s FDA approval, the U.S. Centers for […]
As COVID-19 infections threatened to overwhelm hospitals in March 2020, infection control specialists worried not just about SARS-CoV-2 but also about other viral, bacterial and fungal diseases. C. auris is a type of fungus that causes severe, often fatal infections and is resistant to most antifungal drugs. It can be carried on a patient’s skin and can survive on surfaces for […]
Journal of Clinical Investigation The discovery that multiciliated cells in the nasal epithelium are the first cells to be targeted in early COVID-19 infection might provide the rationale for treatment using suitable antiviral nasal sprays. Led by Director KOH Gou Young, scientists from the Center for Vascular Research within the Institute for Basic Science, South Korea, have recently uncovered the […]
Scientists isolated a molecule, extracted from the leaves of the European chestnut tree, with the power to neutralize dangerous, drug-resistant staph bacteria. Frontiers in Pharmacology published the finding, led by scientists at Emory University. The researchers dubbed the molecule Castaneroxy A, after the genus of the European chestnut, Castanea. The use of chestnut leaves in traditional folk remedies in rural Italy inspired […]
The oldest strain of Yersinia pestis–the bacteria behind the plague that caused the Black Death, which may have killed as much as half of Europe’s population in the 1300s–has been found in the remains of a 5,000-year-old hunter-gatherer. A genetic analysis publishing June 29 in the journal Cell Reports reveals that this ancient strain was likely less contagious and not as deadly as […]
Two U.S. Phase 1 clinical trials of a novel candidate malaria vaccine have found that the regimen conferred unprecedentedly high levels of durable protection when volunteers were later exposed to disease-causing malaria parasites. The vaccine combines live parasites with either of two widely used antimalarial drugs–an approach termed chemoprophylaxis vaccination. A Phase 2 clinical trial of the vaccine is now […]
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