British sex lives revealed in new study

A new study published today shows the number of sexual partners we have changes as we age – and there are some surprising results. Researchers from the University of East Anglia (UEA), in collaboration with King’s College London and University College London, surveyed more than 5,000 people aged 18 years and older during the 2022 mpox (previously known as “monkeypox”) […]

First RSV vaccine to protect infants and older adults

EU medicines regulators have approved a vaccine to protect against disease caused by the respiratory syncytial virus (RSV). Abrysvo is the first RSV vaccine indicated for passive immunisation of infants from birth through 6 months of age following administration of the vaccine to the mother during pregnancy. This vaccine is also indicated for active immunisation of adults aged 60 years […]

FDA approves Veklury to treat COVID-19 in people with mild to severe hepatic impairment with no dose adjustment – Gilead Sciences

Gilead Sciences, Inc. announced that the FDA approved a supplemental new drug application (sNDA) for the use of Veklury (remdesivir) with no dose adjustments to treat COVID-19 in people with mild, moderate and severe hepatic impairment. This approval further supports the safety profile of Veklury as the first and only approved antiviral COVID-19 treatment that can be used across all […]

Results of phase IV trial (ZOSTER-076) of Shingrix shows efficacy and safety in Herpes Zoster – GSK

GSK announced positive results from the first-ever efficacy trial of Shingrix (Recombinant Zoster Vaccine or RZV) in China. These results come from the post-license phase IV trial (ZOSTER-076), which evaluated the efficacy and safety of RZV in preventing shingles in adults aged 50 and over. The trial included almost 6,000 participants randomised 1:1 to the RZV or placebo group and […]

Scientists find ‘concerning’ flaw in malaria diagnostics

Current methods can vastly overestimate the rates that malaria parasites are multiplying in an infected person’s blood, which has important implications for determining how harmful they could be to a host, according to a new report. The findings also have consequences for understanding the evolution of traits that lead to drug resistance, how quickly a parasite might spread through a […]

Raising awareness of Long Covid ‘blue legs’ symptom

An unusual case of a Long Covid patient’s legs turning blue after 10 minutes of standing highlights the need for greater awareness of this symptom among people with the condition, according to new research published in the Lancet. The paper, authored by Dr Manoj Sivan at the University of Leeds, focuses on the case of one 33-year man who developed with […]

Community health program boosts child vaccinations in remote areas of Madagascar

Madagascar is one of the poorest countries in the world and access to health care is limited for many people. Childhood vaccinations are a crucial component of preventative care, but vaccination rates remain below the World Health Organization’s goal of reaching 95% of children. A new study from the University of Illinois Urbana-Champaign examines the effectiveness of a health intervention program that enlists community-based […]

Janssen submits supplemental new drug application to FDA seeking expanded pediatric indication for HIV-1 therapy Edurant

The Janssen Pharmaceutical Companies of Johnson & Johnson announced the submission of a supplemental New Drug Application (sNDA) to the FDA seeking to expand the indication of Edurant (rilpivirine) to include the treatment of HIV-1 infection in children weighing 10 kg or more. A parallel Marketing Authorization application has also been submitted to the European Medicines Agency (EMA) in support […]

Twice-yearly lenacapavir demonstrates sustained impact on health-related quality of life in people with HIV – Gilead Sciences

Gilead Sciences, Inc. presented new data reinforcing the efficacy, safety, and tolerability profile of lenacapavir, including patient-reported outcomes (PRO) from the Phase II/III CAPELLA trial . These latest findings underscore the role of lenacapavir, the first long-acting injectable HIV treatment medication administered twice-yearly, as a person-centric therapy option and its transformative potential impact on the future of coordinated HIV clinical […]

VBI Vaccines announces PreHevbri is now available in the United Kingdom for the prevention of hepatitis B in adults

VBI Vaccines Inc. announced that PreHevbri [Hepatitis B vaccine (recombinant, adsorbed)] is now available in the United Kingdom for active immunization against infection caused by all known subtypes of the hepatitis B virus (HBV) in adults. It can be expected that hepatitis D will also be prevented by immunization with PreHevbri as hepatitis D (caused by the delta agent) does […]