Synthetic hinge could hold key to revolutionary ‘smart’ insulin therapy

For people with diabetes who are insulin dependent, glycemic control is a full-time job. But what if their medication could do the work for them — an insulin whose activity in the bloodstream responds to the blood glucose levels and adjusts accordingly? An invention from Indiana University School of Medicine Distinguished Professor Michael A. Weiss, MD, PhD, could lead to […]

New Soliqua data shows improved blood sugar control without weight gain versus premixed insulin – Sanofi

A new study of Soliqua (insulin glargine 100 Units/mL and lixisenatide, (iGlarLixi) met its two primary endpoints and all key secondary endpoints in a head-to-head comparison against premixed insulin (biphasic insulin aspart 30, BIAsp 30) in adults living with type 2 diabetes , the most common form of diabetes, uncontrolled on insulin and one or two oral anti-diabetic medicines. The […]

Metabolic hormone ‘leptin’ linked to poor vaccine response

Reduced levels of a metabolic hormone known as leptin is linked to poor vaccine antibody responses in the general population, a University of Queensland study has found. The researchers made the discovery while investigating several cohorts’ responses to the influenza vaccine or hepatitis B vaccine pre-COVID. UQ’s Professor Di Yu identified a link between the metabolic and immune systems that […]