People with early-stage Hodgkin lymphoma face a higher risk of dying from cardiovascular disease than from cancer

Treatment advances have improved the survival of individuals with Hodgkin lymphoma (HL)—a type of cancer that affects the lymphatic system—but therapies can increase patients’ risk of developing heart problems. A recent study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, reveals that people with early-stage HL are now at higher risk of dying from cardiovascular disease than […]

AI speeds sepsis detection to prevent hundreds of deaths

Patients are 20% less likely to die of sepsis because a new AI system developed at Johns Hopkins University catches symptoms hours earlier than traditional methods, an extensive hospital study demonstrates. The system, created by a Johns Hopkins researcher whose young nephew died from sepsis, scours medical records and clinical notes to identify patients at risk of life-threatening complications. The […]

Regular screening of people at high risk for pancreatic cancer pays off

Surveillance programs for people at high risk of developing pancreatic cancers can help detect precancerous conditions and cancers early, when they are most treatable, according to a new multicenter study directed by experts at the Johns Hopkins Kimmel Cancer Center. A total of 1,461 individuals at high risk of developing pancreatic cancer were enrolled in the Cancer of Pancreas Screening-5 (CAPS5) study […]

Leading radiotherapy researchers identify research priorities to improve outcomes for cancer patients

The NCRI Radiotherapy (CTRad) Group, a world-leading radiotherapy research group, has published its strategic priorities in radiotherapy research to address challenges in the field. The group has identified four strategic priorities it believes need to be addressed by the community to improve outcomes for patients: Translating novel discoveries to and from the clinic Evaluating and optimal implementation of new radiotherapy […]

Brentuximab vedotin may improve overall survival in patients with Hodgkin Lymphoma

A study led by researchers from Mayo Clinic Comprehensive Cancer Center has found that the addition of brentuximab vedotin to standard chemotherapy treatment improves overall survival in patients with Hodgkin Lymphoma, when compared to the current standard of chemotherapy alone. Results of the research were presented by Stephen Ansell, M.D., Ph.D., at the 2022 American Society of Clinical Oncology Annual Meeting (ASCO) in Chicago […]

Adults with blood cancers respond to booster, not initial dose of COVID-19 vaccine

People with hematologic malignancies—or blood cancers including leukemia, lymphoma, and multiple myeloma—have an impaired immune system due to their disease and its treatment, putting them at risk of severe COVID-19 infection and experiencing a reduced response to COVID-19 vaccination. In a recent study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, less than half of patients with […]

Bariatric surgery cuts cancer risks significantly

Obese adults who lost weight through bariatric surgery have achieved a significantly reduced risk of cancer and cancer-related death compared with obese adults who did not have such surgery. The research was published on June 2, 2022 in JAMA. Ali Aminian, M.D., lead author of the study and director of Cleveland Clinic’s Bariatric & Metabolic Institute in Cleveland, Ohio, said, “Patients […]

Positive results from phase III PRIME study of Zejula at Society of Gynecologic Oncology Meeting – Zai Lab + GSK

Zai Lab Limited presented data from the Phase III PRIME study of Zejula (niraparib) as maintenance therapy at the Society of Gynecologic Oncology annual meeting . Zejula demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS) with a tolerable safety profile in Chinese patients with newly diagnosed advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer (collectively […]

CHMP recommends Opdivo for the adjuvant treatment of adults with muscle-invasive urothelial carcinoma – BMS

Bristol Myers Squibb announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended approval of Opdivo (nivolumab) for the adjuvant treatment of adults with muscle-invasive urothelial carcinoma with tumor cell PD-L1 expression greater than 1% who are at a high risk of recurrence after undergoing radical resection. The European Commission (EC), […]