Survival rates similar with different treatments of localized prostate cancer

Patients who chose active monitoring of their localized prostate cancer have achieved the same high survival rates as those who chose radiotherapy or surgery. Researchers reported these findings on March 11, 2023 in the New England Journal of Medicine. Lead investigator Freddie Hamdy, MD,  Professor of Surgery, Professor of Urology and Head of the Nuffield Department of Surgical Sciences at […]

Adjunctive antipsychotic treatment appears to help elderly with treatment-resistant depression

Among patients over 60 with treatment-resistant depression, adding the antipsychotic drug aripiprazole (Abilify) to their treatment appears to be a more effective strategy than switching antidepressants. Researchers reported these findings on March 3, 2023 in the New England Journal of Medicine. “Often, unless a patient responds to the first treatment prescribed for depression, physicians follow a pattern in which they […]

Single dose of azithromycin reduces maternal sepsis or death

Ten percent of maternal deaths are caused by infections that occur shortly before, during or after delivery. Maternal infections and sepsis, which is a serious complication of infections, are among the top five causes of maternal mortality worldwide. Maternal infection also increases the risk of neonatal sepsis, which accounts for 16 percent of newborn deaths. A new study published today in the New […]

NIH experts review monkeypox challenges

Lessons learned from the public health responses to the HIV and COVID-19 pandemics should help guide the response to the current outbreak of monkeypox, National Institutes of Health experts write in an editorial published today in the New England Journal of Medicine. Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), and H. Clifford Lane, […]

Troponin emerges as marker of death risk after cardiac surgery

Canadian researchers report that troponin levels after cardiac surgery could be a significant marker for 30-day mortality risk. Their findings were published on March 2, 2022 in the New England Journal of Medicine. “This study is a landmark for the health teams taking care of patients after cardiac surgery. For the first time, we have a marker that is fast […]

Johnson & Johnson single-shot COVID-19 vaccine phase III data published in New England Journal of Medicine

Johnson & Johnson announced publication in the New England Journal of Medicine of primary data from the Phase III ENSEMBLE clinical trial for its single-dose COVID-19 vaccine, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen). The publication of the primary analysis follows the topline efficacy and safety data announced in January, showing the trial met all primary […]