Soliris approved in China for the treatment of adults with refractory generalised myasthenia gravis – AstraZeneca

Soliris (eculizumab) has been approved in China for the treatment of adult patients with refractory generalised myasthenia gravis (gMG) who are anti-acetylcholine receptor (AChR) antibody-positive. Soliris is the first and only complement inhibitor approved for the treatment of gMG in China. The approval by the National Medical Products Administration (NMPA) in China was based on comprehensive results from the Phase […]

EU approves Briumvi in adults with relapsing multiple sclerosis – TG Therapeutics

TG Therapeutics announced that the European Commission (EC) has granted approval of Briumvi (ublituximab xiiy) for the treatment of adult patients with relapsing forms of multiple sclerosis (RMS) with active disease defined by clinical or imaging features. Briumvi was granted approval by the FDA on December 28, 2022, for the treatment of RMS in adults. Briumvi is the first and […]

Drug significantly reduces chorea symptoms in patients with Huntington’s disease

The drug valbenazine statistically improves chorea, a movement disorder commonly associated with Huntington’s disease, when compared to a placebo, according to a recent international study led by UTHealth Houston researcher Erin Furr Stimming, MD, who served as principal investigator on behalf of the KINECT-HD Huntington Study Group. The study results – which were published online today and will appear in the June 2023 print […]

Diabetes drug shows promise for “blinding headache” condition

Exenatide, an injectable treatment for type 2 diabetes, has shown efficacy for the treatment of ‘blinding’ headaches known as idiopathic intercranial hypertension (IIH). Researchers from a phase 2 trial reported the finding on March 12, 2023 in the journal Brain. Lead investigator Alex Sinclair, Professor of Neurology in the Institute of Metabolism and Systems Research at the University of Birmingham […]

Is bone health linked to brain health?

People who have low bone density may have an increased risk of developing dementia compared to people who have higher bone density, according to a study published in the March 22, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that low bone density causes dementia. It only shows an association. “Low […]

Head injury linked to increased risk of death over long-term

Is head injury associated with long-term all-cause mortality risk? Findings from a 30-year follow-up study indicate such an association, researchers reported on Jan 25, 2023 in JAMA Neurology. “Our data reveals that head injury is associated with increased mortality rates even long-term. This is particularly the case for individuals with multiple or severe head injuries,” said lead author, Holly Elser, […]

Why migraine frequently occurs during menstruation

When women suffer migraine attacks, it is often just before or during their monthly period. A team of researchers from Charité – Universitätsmedizin Berlin has now identified a possible explanation. According to their study, published in the journal Neurology,* women who experience migraines have higher levels of CGRP during menstruation. CGRP is a neurotransmitter that is known to play an important […]

Migraine: how to diagnose, manage and prevent

Migraine is a major cause of disability, affecting about 12% of people. A 2-part series published in CMAJ (Canadian Medical Association Journal) on diagnosing and managing the condition with both acute and preventive therapy provides guidance for clinicians https://www.cmaj.ca/lookup/doi/10.1503/cmaj.211969. “The goal of treatment of migraine attacks is to provide rapid relief from pain and other migraine-related symptoms, to restore patient function and […]

Six minutes of high-intensity exercise could delay the onset of Alzheimer’s disease

Six minutes of high-intensity exercise could extend the lifespan of a healthy brain and delay the onset of neurodegenerative disorders, such as Alzheimer’s disease and Parkinson’s disease. New research published in The Journal of Physiology shows that a short but intense bout of cycling increases the production of a specialised protein that is essential for brain formation, learning and memory, and could […]