Galapagos concludes strategic evaluation and signs letter of intent to transfer Jyseleca business to Alfasigma

Galapagos NV and Alfasigma S.p.A. announced that they have signed a letter of intent contemplating a transfer of the Jyseleca business to Alfasigma, including the European and UK Marketing Authorizations, the commercial, medical and development activities for Jyseleca and approximately 400 positions in 14 European countries. In the contemplated transaction, Galapagos will receive a €50 million upfront, potential milestone payments […]

Beyond use dating of nanoparticle albumin-bound paclitaxel (Pazenir) infusion

Prepared infusions of nanoparticle albumin-bound (nab) paclitaxel are stable for seven days, when stored in a refrigerator, according to researcher Helen Linxweiler (University Medical Centre of Johannes Gutenberg University, Mainz, Germany). Paclitaxel is widely used in cancer chemotherapy e.g. for treatment of metastatic breast, pancreas and lung cancer. The nab formulation has to be reconstituted and diluted in a carrier […]

Antibiotics for common childhood infections no longer effective

Drugs to treat common infections in children and babies are no longer effective in large parts of the world, due to high rates of antibiotic resistance. The University of Sydney led study found many antibiotics recommended by the World Health Organization (WHO) had less than 50 percent effectiveness in treating childhood infections such as pneumonia, sepsis (bloodstream infections) and meningitis. […]

Study shows simple diet swaps can cut carbon emissions and improve your health

Curbing carbon emissions and eating healthier may both start at the dinner table. According to a new study co-authored by a Tulane University researcher and published in the journal Nature Food, making simple substitutions like switching from beef to chicken or drinking plant-based milk instead of cow’s milk could reduce the average American’s carbon footprint from food by 35%, while also boosting […]

Number of dementia cases could be 42% higher than previously estimated by 2040

Up to 1.7 million people could be living with dementia in England and Wales by 2040 – over 40% more than previously forecast – finds a new UCL-led study. Previous studies, based on data up to 2010, showed that dementia incidence had declined in high-income countries. However, the new research, published in The Lancet Public Health, indicates that dementia incidence started […]

Simple blood test can help diagnose bipolar disorder

Researchers have developed a new way of improving diagnosis of bipolar disorder that uses a simple blood test to identify biomarkers associated with the condition. The researchers, from the University of Cambridge, used a combination of an online psychiatric assessment and a blood test to diagnose patients with bipolar disorder, many of whom had been misdiagnosed with major depressive disorder. […]

What the papers say – weekly digest (27/10/23)

Your weekly digest of the top healthcare stories, covering news published from 23/10/2023 – 27/10/2023. Daily Express More than half England’s authorities are failing to meet national dementia diagnosis targets. A postcode lottery means hundreds of thousands do not have the confirmation they need to obtain new treatments, Parliament’s all-party group on dementia said. Its report said a diagnosis rate […]

Examining sexual health equity in emergency care

Research from experts at Michigan Medicine is highlighting the potential for additional at-home assistance for partners of those who are treated in the emergency department  for a sexually transmitted infection. Expedited partner therapy is one method of reducing STI re-infection. It’s  a safe, effective, harm-reduction-focused practice of treating sex partner(s) of patients with STIs without a clinical exam of the partner(s). This […]

Predictors of opioid overdose after prescription for chronic pain

A large study published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.230459 identified 10 predictors of opioid overdose after prescription for chronic pain, which can help clinicians engage in shared decision-making with patients around opioid prescribing. “The opioid crisis has generated interest in identifying patients at higher risk of addiction or overdose and has led to the development of several screening tools; however, these instruments […]