Palliative care is underused for patients with malignant urinary obstruction

Less than half of patients with malignant ureteral obstruction (MUO) – a serious complication of advanced cancer, with a poor prognosis – receive palliative care (PC) for their condition, reports a paper in the January issue of Urology Practice®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer. Hospice care can promote patient comfort while […]

CHMP recommends Velsipity (etrasimod) for the treatment of ulcerative colitis – Pfizer

On 14 December 2023, the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation for the medicinal product Velsipity, intended for the treatment of ulcerative colitis. The applicant for this medicinal product is Pfizer Europe. Velsipity will be available as a 2 mg film-coated tablet. The active substance of Velsipity […]

Diabetes drugs appear to lower colorectal cancer risk

Glucagon-like receptor agonists (GLP-1 RAs), a class of type 2 diabetes drug treatments, appear to also reduce the risk of colorectal cancer (CRC) researchers reported on Dec. 7, 2023 in JAMA Oncology. “Our results clearly demonstrate that GLP-1 RAs are significantly more effective than popular anti-diabetic drugs, such as Metformin or insulin, at preventing the development of CRC,” said co-lead […]

A free online tool can help prostate cancer patients save on out-of-pocket drug costs

A free online tool could potentially save some prostate cancer patients more than $9,000 in out-of-pocket drug costs, a new study finds. For patients enrolled in Medicare Part D prescription drug plans, out of pocket costs can vary significantly. But by using an online Medicare plan finder tool, patients can compare pricing among all Part D drug plans offered in […]

European Commission approves Lonsurf in combination with bevacizumab for the third-line treatment of metastatic colorectal cancer – Servier + Taiho

Taiho Pharmaceutical announced that its partner Servier, has won European regulatory approval for Lonsurf (trifluridine + tipiracil) in combination with bevacizumab for the third-line treatment of metastatic colorectal cancer (mCRC). The European Commission gave its approval to the combination therapy in adult patients with mCRC who have received two prior anticancer treatment regimens, including fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapies, anti-VEGF […]

First-line Opdivo plus chemotherapy provides survival benefit in metastatic urothelial carcinoma (bladder cancer) – BMS

Frontline treatment with the combination of nivolumab (Opdivo) and cisplatin-based chemotherapy, followed by nivolumab monotherapy, led to a statistically significant improvement in progression-free survival (PFS) and overall survival (OS) compared with standard cisplatin-based chemotherapy regimens alone in previously untreated, cisplatin-eligible patients with unresectable or metastatic urothelial carcinoma, according to data from the phase III CheckMate-901 trial (NCT03036098). The study met […]

Publication of phase III FRESCO-2 results evaluating fruquintinib in patients with previously treated colorectal cancer in The Lancet – Takeda and HutchMed

Takeda and HUTCHMED (China) Limited announced that results of the Phase III FRESCO2 study evaluating fruquintinib in patients with previously treated metastatic colorectal cancer (CRC) were published in The Lancet.The publication provides details of the FRESCO-2 study results as of June 24, 2022. Summary results from this cut-off date were presented on September 12, 2022, at the European Society for […]

Survival rates similar with different treatments of localized prostate cancer

Patients who chose active monitoring of their localized prostate cancer have achieved the same high survival rates as those who chose radiotherapy or surgery. Researchers reported these findings on March 11, 2023 in the New England Journal of Medicine. Lead investigator Freddie Hamdy, MD,  Professor of Surgery, Professor of Urology and Head of the Nuffield Department of Surgical Sciences at […]

Study finds certain substances in urine, blood can predict kidney disease progression

In a new study looking at the long-term effects of hospitalized patients who have acute kidney injury (AKI), a sudden but temporary loss of kidney function, Johns Hopkins Medicine researchers found that higher levels of certain biomarkers in urine and blood can predict a patient’s risk of developing chronic kidney disease (CKD). The findings, published on March 23, in the Journal […]

UK study finds vasectomies are even safer than reported

Vasectomies are much less likely to cause complications than expected, according to a new UK study reviewing the outcomes from over 90,000 vasectomies performed over 15 years. The study, led by researchers from Gloucestershire Hospitals NHS Foundation Trust, is being presented today at the European Association of Urology (EAU) Congress in Milan. It shows that existing leaflets explaining the potential […]