Esketamine shows higher efficacy than quetiapine in treatment-resistant depression

Researchers report that patients treated for treatment-resistant depression with esketamine NS (nasal spray), a form of ketamine, achieve better and more durable outcomes than similar patients treated with quetiapine. The findings were published on October 5 in the New England Journal of Medicine and presented the same week at the annual meeting of the European College of Neuropsychopharmacology. “This is […]

Adjunctive antipsychotic treatment appears to help elderly with treatment-resistant depression

Among patients over 60 with treatment-resistant depression, adding the antipsychotic drug aripiprazole (Abilify) to their treatment appears to be a more effective strategy than switching antidepressants. Researchers reported these findings on March 3, 2023 in the New England Journal of Medicine. “Often, unless a patient responds to the first treatment prescribed for depression, physicians follow a pattern in which they […]