Tonsillectomy both clinically and cost effective for adults

Scientists say tonsil removal is both clinically and cost effective for adults who get recurrent severe sore throats. The biggest study of its kind, carried out by Newcastle University, revealed that patients who had a tonsillectomy had 50% less sore throats over two years, compared to patients who did not undergo tonsillectomy. Publishing today (17 May) in The Lancet, the study […]

An estimated one million stillbirths and newborn baby deaths could be prevented each year by implementing low-cost pregnancy interventions in low- and middle-income countries

Eight low-cost and easily implementable proven interventions for pregnant women in 81 low- and middle-income countries (LMICs) could prevent an estimated 566,000 stillbirths and 5.2 million babies a year from being born preterm or small for gestational age—some with low birth weight—the impacts of which would also affect long-term health and economic output, says a new four-paper Series published in The […]

For NASH, bariatric surgery is more effective than drug treatment or lifestyle intervention

Bariatric surgery treats advanced non-alcoholic fatty liver disease (NASH) significantly more effectively than drug or lifestyle intervention, researchers reported on April 20, 2023 in The Lancet. Professor Francesco Rubino, MD, a senior co-investigator and Chair of Bariatric and Metabolic Surgery at King’s College in London said, “The presence of NASH predicts a significant risk of complications and mortality in people […]

Monthly injections of fitusiran reduces bleeds in patients with haemophilia A and B

Monthly prophylactic injections of fitusiran are effective in reducing bleeds in patients with haemophillia A or B, according to randomised controlled trials publishing simultaneously in The Lancet and The Lancet Haematology journals. Haemophilia is a lifelong, inherited bleeding disorder, which mostly affects men and results in patients with haemophilia A or B missing partially or completely different clotting factor – natural proteins that help […]

Experts pave the way for safer surgery to address global elective waiting lists

Surgical care experts have today unveiled two studies in The Lancet that will help to provide safer surgery for thousands of patients around the world — particularly in Low- and Middle-income Countries (LMIC). Researchers found that routinely changing gloves and instruments just before closing wounds could significantly reduce Surgical Site Infection (SSI) — the world’s most common post-operative complication. Secondly, they tested […]

Meta-analysis shows low risk of muscle pain from statins

In over 90% of cases, statin therapy is not related to muscle pain, researchers from a large new study reported on August 29, 2022 in The Lancet. “The idea that statins may cause frequent muscle pain has been a persistent belief among some patients and clinicians, however our study confirms that the statin is rarely the cause of muscle pain […]

Study reports first use of antivirals in monkeypox patients, highlighting challenges in understanding and treating this rare disease

Peer-reviewed/ Case study/ People An analysis of seven cases of monkeypox that occurred in the UK between 2018-2021 reports on the first instances of in-hospital transmission and household transmission outside of Africa. All patients in the study recovered following treatment in isolation in UK hospital units. Researchers observed patient responses to two different antiviral medications (brincidofovir and tecovirimat), suggesting that […]

How can mental health professionals open their minds to psychosis?

Effective clinical care for patients with psychosis means understanding the ‘lived experience’ of their delusions, say researchers at the Universities of Birmingham, York and Melbourne. By understanding the intricacies of feelings, attitudes, and experiences which are interlinked with delusions, clinicians will be better able to build trust and genuine engagement with patients. In a new study, published today (4 May […]

Ebola Vaccine Regimen demonstrated robust and durable immune response in adults and children in data published in The Lancet Infectious Diseases – Johnson & Johnson

Data from two papers published in The Lancet Infectious Diseases demonstrated that the Johnson & Johnson (the Company) Ebola vaccine regimen, Zabdeno (Ad26.ZEBOV) and Mvabea (MVA-BN-Filo), generated robust humoral (antibody) immune responses in adults and children (ages 1-17) with the immune responses persisting in adults for at least two years. The data also showed that booster vaccination with Ad26.ZEBOV, administered […]