New guideline introduces recommendations for optimal timing of elective hip or knee arthroplasty

The American College of Rheumatology (ACR) and the American Association of Hip and Knee Surgeons (AAHKS) released a summary of its new guideline titled “the Optimal Timing of Elective Hip or Knee Arthroplasty for Patients with Symptomatic Moderate to Severe Osteoarthritis or Osteonecrosis Who Have Failed Nonoperative Therapy.” The ACR and AAHKS have worked together before, creating guidelines for Perioperative Management […]

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

Genicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduce pain, especially for adults who are 50 and older, according to new research to be presented at the Society of Interventional Radiology Annual Scientific Meeting in Phoenix. This is the first time a study has examined patient demographics, […]

New breakthrough in the treatment of rheumatoid arthritis

A research team, led by Professor Sung Ho Park in the Department of Biological Sciences at UNIST announced the results of a study on osteoblasts that damage joint bones in patients with rheumatoid arthritis. In this study, the research team studied the possibility of a treatment method targeting mechanisms related to the differentiation process of osteoblasts that melt bones through enzyme […]

New drug offers hope for people with hand osteoarthritis

Tonia Vincent, Professor of Musculoskeletal Biology & Honorary Rheumatologist at Oxford’s Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), said: ‘Hand osteoarthritis is a common and debilitating medical condition that affects mainly women, especially around the time of the menopause. We currently have no effective treatments that modify their disease.’ The researchers started by investigating a common gene variant […]

Trial shows benefits of two forms of ankle surgery for osteoarthritis

Patients with advanced ankle osteoarthritis who undergo surgery see equally good outcomes from the two main surgical treatments for osteoarthritis, a new study led by UCL researchers has shown. The TARVA randomised clinical trial compared total ankle joint replacement with ankle fusion (when the ankle joint is pinned to prevent movement). It was led by the Comprehensive Clinical Trials Unit […]

Study examines total knee replacement in patients under 21

A new study from researchers at Hospital for Special Surgery (HSS) has evaluated trends in the use of total knee arthroplasty (TKA) in patients under 21 in the United States. The study was reported at the American College of Rheumatology (ACR) Convergence 2022 meeting (abstract number 08780). According to Cynthia A. Kahlenberg, MD, MPH, an orthopedic surgeon at HSS and a […]

Anifrolumab shows long-term promise in patients with lupus

Type I interferon (IFN) is a powerful immune activator that is present at high levels in the majority of patients with lupus, an autoimmune disease. In Arthritis & Rheumatology, researchers report positive results from the first placebo-controlled long-term trial of anifrolumab—a human monoclonal antibody that targets the type I IFN receptor—in patients with lupus. In the long-term extension trial of two […]

Nerve blocks show efficacy in knee osteoarthritis

Researchers report that patients with knee osteoarthritis have achieved significant short-term pain relief with ultrasound-guided genicular nerve blocks (GNB), locally injected anesthetics that block nerves around the knee joint. The findings were published on Nov. 12, 2022 in Arthritis & Rheumatology. “This study demonstrates that genicular nerve block is an effective short-term therapy for pain management in people with knee […]

Getting under the skin of an autoimmune disorder

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital. A subset of these cells, according to the study, may lie at the origins of […]

Rheumatic fever and household overcrowding

Research led by the University of Otago in New Zealand has uncovered the strongest evidence yet that household overcrowding is a major risk factor for acute rheumatic fever and streptococcal infections of the skin. Their research is published in two companion articles in the international medical journal The Lancet Regional Health — Western Pacific. Lead researcher Professor Michael Baker of the […]