Digital health systems can tell clinicians when someone’s heart-disease risk calls for a drug to lower cholesterol or whether insulin shots are warranted for a person with type 2 diabetes. But for millions of low-back pain sufferers, care decisions rely heavily on subjective measures of patient discomfort – often leading to expensive tests and treatments (back pain is the third-highest U.S. health care […]
In over 90% of cases, statin therapy is not related to muscle pain, researchers from a large new study reported on August 29, 2022 in The Lancet. “The idea that statins may cause frequent muscle pain has been a persistent belief among some patients and clinicians, however our study confirms that the statin is rarely the cause of muscle pain […]
Opioids are the gold standard for treatment of chronic and acute pain; however, their use may result in significant gastrointestinal side effects, including nausea, vomiting, and constipation. The reasons behind these side effects are not well understood. A new study in The American Journal of Pathology, published by Elsevier, is the first report of how opioids like morphine cause gastric inflammation […]
Heron Therapeutics, Inc., announced that Health Canada has issued a Notice of Compliance (NOC) to commercialize Zynrelef (bupivacaine and meloxicam extended-release solution) for instillation into the surgical wound for postoperative analgesia after bunionectomy, open inguinal herniorrhaphy, and total knee arthroplasty surgical procedures. Based on prior agreements with the FDA, Heron already has clinical studies underway, which it plans to submit […]
Most people who get a prescription for opioid painkillers to ease the pain of an operation or dental procedure fill it right away. But a new study shows that some fill these prescriptions more than a month later – long after the acute pain from their care should have subsided. In 2019, 1% of opioid prescriptions from dentists and surgeons […]
Millions of consumers and patients around the world will be heartened by the results of the latest study on cannabis and driving. The University of Sydney-led research finds that 1500mg, the highest daily medicinal dose of cannabidiol (CBD), has no impact on people’s driving or cognitive abilities. CBD is a cannabis component widely used for medical as well as ‘wellness’ […]
Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin are widely used to treat pain and inflammation. But even at similar doses, different NSAIDs can have unexpected and unexplained effects on many diseases, including heart disease and cancer. Now, a new Yale-led study has uncovered a previously unknown process by which some NSAIDs affect the body. The finding may explain […]
Researchers have developed a new national blueprint to help health professionals support the one in five Australians living with chronic pain, costing the Australian economy $139 billion every year. Published in leading international interdisciplinary pain journal PAIN, the ‘Listen to me, learn from me’ framework was co-developed by a national team of Curtin University-led researchers and collaborators working in partnership with […]
Leicester researchers are working with NHS partners in the East of England to lead the way in delivering the NHS’ goal of halving the amount of opioids prescribed for non-cancer pain by 2024. Opioids, like morphine and fentanyl, can be effective for short-term management of severe pain. However, they are highly addictive which makes stopping difficult, yet long-term use is […]
Drug misuse is not exclusive to the opioid epidemic, according to a recent West Virginia Universitystudy. Every year, about 50,000 people in the United States are admitted to the emergency room due to misuse of a common over-the-counter pain medication – acetaminophen. With that in mind, Mark Garofoli, director of experiential learning at the WVU School of Pharmacy, spearheaded research that revealed that the public’s […]
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