Patients with rheumatic and musculoskeletal conditions are vulnerable to long term opioid use, with up to 1 in 3 of those with rheumatoid arthritis or fibromyalgia, who take these drugs for the first time, potentially at risk, suggest the findings of a research letter, published online in the Annals of the Rheumatic Diseases. People with rheumatic and musculoskeletal conditions are often […]
Medicinal cannabis can safely relieve cancer pain, while curbing the total number of meds and opioids taken, suggest the results of a multicentre registry study, published online in BMJ Supportive & Palliative Care. Products with an equal balance of the active ingredients tetrahydrocannabinol (THC) and cannabidiol (CBD), rather than a dominance of either one, seem to be particularly effective, the data […]
Recruiting osteoarthritis patients with a lot of pain to clinical studies, may give incorrect results if the researcher does account for the natural variation in pain that occurs. A research group from Lund University in Sweden is now drawing attention to the traps in clinical studies on osteoarthritis. Osteoarthritis is a lifelong joint disease that is becoming increasingly common. The […]
Researchers report that patients who knowingly took a “sugar pill” placebo along with daily methadone treatment achieved significantly higher 90-day adherence to treatment for opioid abuse disorder than patients using only methadone. The findings were published on April 12 in JAMA Network Open. “The clinical implications of our intervention have great potential impact, as retention in treatment is a serious […]
Researchers measured the associations among process, outcomes and patient satisfaction within general medical care for chronic low back pain, provided through an ongoing patient-physician relationship. They also used two models to measure factors associated with patient satisfaction, including studying a subgroup of participants experiencing chronic low back pain who were being treated by the same physician for more than five […]
Genicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduce pain, especially for adults who are 50 and older, according to new research to be presented at the Society of Interventional Radiology Annual Scientific Meeting in Phoenix. This is the first time a study has examined patient demographics, […]
A minimally invasive treatment that injects allograft disc tissue into the spine to relieve pain associated with degenerative disc disease provides significant improvement in pain and function over a sustained period, according to new research to be presented at the Society of Interventional Radiology Annual Scientific Meeting in Phoenix. The treatment, known as viable disc allograft supplementation, injects specialized cells […]
When women suffer migraine attacks, it is often just before or during their monthly period. A team of researchers from Charité – Universitätsmedizin Berlin has now identified a possible explanation. According to their study, published in the journal Neurology,* women who experience migraines have higher levels of CGRP during menstruation. CGRP is a neurotransmitter that is known to play an important […]
Acute low back pain is a common cause of disability. An analysis in the Journal of Orthopaedic Research examined which non-opioid drugs are best for treating this condition. The analysis, which included all randomized controlled trials published to date (18 studies with 3,478 patients), showed that muscle relaxants and non-steroidal anti-inflammatory drugs (NSAIDs) could effectively and rapidly reduce symptoms. The combination of […]
Migraine is a major cause of disability, affecting about 12% of people. A 2-part series published in CMAJ (Canadian Medical Association Journal) on diagnosing and managing the condition with both acute and preventive therapy provides guidance for clinicians https://www.cmaj.ca/lookup/doi/10.1503/cmaj.211969. “The goal of treatment of migraine attacks is to provide rapid relief from pain and other migraine-related symptoms, to restore patient function and […]
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