Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

Genicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduce pain, especially for adults who are 50 and older, according to new research to be presented at the Society of Interventional Radiology Annual Scientific Meeting in Phoenix. This is the first time a study has examined patient demographics, […]

Injectable tissue provides significant, long-term relief for chronic back pain

A minimally invasive treatment that injects allograft disc tissue into the spine to relieve pain associated with degenerative disc disease provides significant improvement in pain and function over a sustained period, according to new research to be presented at the Society of Interventional Radiology Annual Scientific Meeting in Phoenix. The treatment, known as viable disc allograft supplementation, injects specialized cells […]

Why migraine frequently occurs during menstruation

When women suffer migraine attacks, it is often just before or during their monthly period. A team of researchers from Charité – Universitätsmedizin Berlin has now identified a possible explanation. According to their study, published in the journal Neurology,* women who experience migraines have higher levels of CGRP during menstruation. CGRP is a neurotransmitter that is known to play an important […]

Which medications are best for treating acute low back pain?

Acute low back pain is a common cause of disability. An analysis in the Journal of Orthopaedic Research examined which non-opioid drugs are best for treating this condition. The analysis, which included all randomized controlled trials published to date (18 studies with 3,478 patients), showed that muscle relaxants and non-steroidal anti-inflammatory drugs (NSAIDs) could effectively and rapidly reduce symptoms. The combination of […]

Migraine: how to diagnose, manage and prevent

Migraine is a major cause of disability, affecting about 12% of people. A 2-part series published in CMAJ (Canadian Medical Association Journal) on diagnosing and managing the condition with both acute and preventive therapy provides guidance for clinicians https://www.cmaj.ca/lookup/doi/10.1503/cmaj.211969. “The goal of treatment of migraine attacks is to provide rapid relief from pain and other migraine-related symptoms, to restore patient function and […]

People with arthritis 20% less likely to be in work

The typical person living with arthritis in the UK is 20% less likely to be in work than their equivalent without the condition, new research shows. And the most striking finding was that non-university educated women aged 60-plus are at least 37% less likely to be in work if they have arthritis, compared to matched individuals without the condition. The […]

Overdose deaths involving buprenorphine did not proportionally increase with new flexibilities in prescribing

The proportion of opioid overdose deaths involving buprenorphine, a medication used to treat opioid use disorder, did not increase in the months after prescribing flexibilities were put in place during the COVID-19 pandemic, according to a new study. These data provide evidence that may help to inform buprenorphine prescribing policies. Published today in JAMA Network Open, this study was a collaborative effort […]

Pharmacists can start patients on road to recovery from opioid use disorder

A study from researchers at Brown University, Rhode Island Hospital and the University of Rhode Island found that pharmacists — not just physicians at clinics and doctor’s offices — can safely and effectively start patients with opioid use disorder on the lifesaving medication buprenorphine. “With over 100,000 overdose deaths in 2022 and an opioid crisis impacting states across the country, […]

Wastewater samples show the dramatic effects of tough love on codeine addicts as consumption plunges

Switching the painkiller codeine to a prescription-only medicine in 2018 led to a 37 per cent overall drop in its consumption across Australia, according to new findings from wastewater sampling published in the journal Addiction. The samples, taken from 49 wastewater treatment plants, which cover catchment areas for 10.6 million Australians, show the dramatic effect of withdrawing the country’s most misused […]

Treating gut pain via a Nobel prize-winning receptor

Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon, led by Professor Hongzhen Hu at Washington University and Professor Nick Spencer at Flinders University, […]