Pain is no joke in labor, but withdrawing laughing gas has no ill effects

Birthing women denied nitrous oxide (‘laughing gas’) to relieve labour pain during the COVID-19 pandemic have turned to opioids instead, without any adverse outcomes for mother or child, according to a new study by Australian clinicians. The study, at Lyell McEwin Hospital in Adelaide, looked at the impact of withholding nitrous oxide (N20), a decision adopted by numerous hospitals worldwide in the […]

New study confirms that postoperative pain can be reduced with NOL guided analgesia

A new study has found that monitoring pain response levels during surgery with NOL technology (Medasense, Ramat Gan, Israel) can help reduce postoperative pain. Exploring the clinical effect of NOL guided fentanyl dosing on post-operative pain, the study demonstrated that patient pain scores after surgery were 30% lower when administration of pain medication during surgery was guided with NOL monitoring. […]

How new motion-sensing technology may help standardize back-pain care

Digital health systems can tell clinicians when someone’s heart-disease risk calls for a drug to lower cholesterol or whether insulin shots are warranted for a person with type 2 diabetes. But for millions of low-back pain sufferers, care decisions rely heavily on subjective measures of patient discomfort – often leading to expensive tests and treatments (back pain is the third-highest U.S. health care […]

Meta-analysis shows low risk of muscle pain from statins

In over 90% of cases, statin therapy is not related to muscle pain, researchers from a large new study reported on August 29, 2022 in The Lancet. “The idea that statins may cause frequent muscle pain has been a persistent belief among some patients and clinicians, however our study confirms that the statin is rarely the cause of muscle pain […]

New study sheds light on why opioids can cause gastrointestinal problems

Opioids are the gold standard for treatment of chronic and acute pain; however, their use may result in significant gastrointestinal side effects, including nausea, vomiting, and constipation. The reasons behind these side effects are not well understood. A new study in The American Journal of Pathology, published by Elsevier, is the first report of how opioids like morphine cause gastric inflammation […]

Approval of Zynrelef by Health Canada for the management of postoperative pain – Heron Therapeutics

Heron Therapeutics, Inc., announced that Health Canada has issued a Notice of Compliance (NOC) to commercialize Zynrelef (bupivacaine and meloxicam extended-release solution) for instillation into the surgical wound for postoperative analgesia after bunionectomy, open inguinal herniorrhaphy, and total knee arthroplasty surgical procedures. Based on prior agreements with the FDA, Heron already has clinical studies underway, which it plans to submit […]

Could time limits on opioid prescriptions reduce misuse?

Most people who get a prescription for opioid painkillers to ease the pain of an operation or dental procedure fill it right away. But a new study shows that some fill these prescriptions more than a month later – long after the acute pain from their care should have subsided. In 2019, 1% of opioid prescriptions from dentists and surgeons […]

Very high doses of CBD, a cannabis component, don’t affect driving

Millions of consumers and patients around the world will be heartened by the results of the latest study on cannabis and driving. The University of Sydney-led research finds that 1500mg, the highest daily medicinal dose of cannabidiol (CBD), has no impact on people’s driving or cognitive abilities. CBD is a cannabis component widely used for medical as well as ‘wellness’ […]

New research may explain unexpected effects of common painkillers

Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin are widely used to treat pain and inflammation. But even at similar doses, different NSAIDs can have unexpected and unexplained effects on many diseases, including heart disease and cancer. Now, a new Yale-led study has uncovered a previously unknown process by which some NSAIDs affect the body. The finding may explain […]

New health professional training blueprint to transform chronic pain care

Researchers have developed a new national blueprint to help health professionals support the one in five Australians living with chronic pain, costing the Australian economy $139 billion every year. Published in leading international interdisciplinary pain journal PAIN, the ‘Listen to me, learn from me’ framework was co-developed by a national team of Curtin University-led researchers and collaborators working in partnership with […]