First new treatment for osteoporosis for over a decade

Thousands of people in England and Wales with severe osteoporosis who are at high risk of fracture are set to benefit from a new treatment – romosozumab (Evenity™, UCB) – after NICE recommended it for people after menopause in final draft guidance published on 1st April by NICE. Over 20,000 people could be eligible for the treatment according to the […]

AI helps radiologists detect bone fractures

Artificial intelligence (AI) is an effective tool for fracture detection that has potential to aid clinicians in busy emergency departments, according to a study in Radiology. Missed or delayed diagnosis of fractures on X-ray is a common error with potentially serious implications for the patient. Lack of timely access to expert opinion as the growth in imaging volumes continues to outpace […]

Mayo Clinic discovery in bone marrow cancer points to potential drug targets

New research from Mayo Clinic’s Center for Individualized Medicine finds that patients with ASXL1-mutant chronic myelomonocytic leukemia — an uncommon type of cancer of the bone marrow — have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster. The ASXL1 genetic mutation also can transform the disease into the more aggressive acute myeloid leukemia. The study, published in Nature Communications, […]

Roche presents new data for Evrysdi at World Muscle Society (WMS) 2021 highlighting new advances for people living with rare neuromuscular disorders

Roche announced data from across its growing neuromuscular portfolio at the World Muscle Society (WMS) Virtual Congress 20 – 24 September 2021. The presentations included additional results from the RAINBOWFISH study, evaluating the efficacy and safety of Evrysdi (risdiplam) in babies with pre-symptomatic spinal muscular atrophy (SMA) from birth to six weeks of age and data. At WMS 2021, data […]

Quadricep muscle contracts differently after ACL reconstruction; may contribute to lingering weakness

After an anterior cruciate ligament reconstruction surgery, it’s common to experience quadriceps weakness, which was thought to be caused primarily by muscle atrophy, or shrinkage. But researchers at the University of Michigan School of Kinesiology have found an additional cause, which could help clinicians design more effective rehabilitation programs. They found that besides muscle loss, the quadricep muscle — specifically, […]

Pre-surgical and post-surgical physical therapy for knee replacement patients lowers risk of chronic opioid use

Physical therapy appears to the lower risk of chronic opioid use among patients undergoing total knee replacement, researchers reported on Oct. 27, 2021 in Physical Medicine and Rehabilitation. The investigators reported that physical therapy within 90 days before or after total knee replacement was associated with lower risk of chronic opioid use. Furthermore, six or more sessions of physical therapy […]