Novel imaging approach reveals important details about rare eye disease choroideremia

By combining traditional eye imaging techniques with adaptive optics – a technology that enhances imaging resolution – researchers at the National Eye Institute (NEI) have shown for the first time how cells across different tissue layers in the eye are affected in people with choroideremia, a rare genetic disorder that leads to blindness. Their study, which was funded by the […]

New diagnostic option for rare eye disease

An estimated five to ten percent of blindness worldwide is caused by the rare inflammatory eye disease uveitis. Posterior uveitis in particular is often associated with severe disease progression and the need for immunosuppressive therapy. In posterior uveitis, inflammation occurs in the retina and in the underlying choroid that supplies it with nutrients. Researchers at the Ophthalmology Department at the […]

“Step therapy” effective for diabetic macular edema

Researchers report that a therapeutic “step strategy,” in which patients with diabetic macular edema begin their treatment with a less expensive drug and, if vision fails to improve, switch to a more expensive medicine, produces similar results to beginning with the more expensive drug. The findings were published on July 14, 2022 in the NEJM/New England Journal of Medicine. “Our […]

Blinding eye disease is strongly associated with heart disease and stroke

Patients with a specific form of age-related macular degeneration (AMD), a leading cause of blindness in the United States, are at significant risk for cardiovascular disease and stroke, according to new research from New York Eye and Ear Infirmary of Mount Sinai. This study, published in the July issue of Retina, is the first to demonstrate a link between the disorders. “For […]

Poor eyesight unfairly mistaken for brain decline

Millions of older people with poor vision are at risk of being misdiagnosed with mild cognitive impairments, according to a new study by the University of South Australia. Cognitive tests that rely on vision-dependent tasks could be skewing results in up to a quarter of people aged over 50 who have undiagnosed visual problems such as cataracts or age-related macular […]

How do our eyes stay focused on what we reach for? Researchers uncover how our gaze is “anchored” in the brain

Keeping our eyes focused on what we reach for, whether it be an item at the grocery store or a ground ball on the baseball field, may appear seamless, but, in fact, is due to a complex neurological process involving intricate timing and coordination. In a newly published study in the journal Nature, a team of researchers sheds additional light on […]

New real-world data show high rate of patient adherence to Tepezza for thyroid eye disease (TED) – Horizon Therapeutics

Horizon Therapeutics plc announced findings of a real-world adherence analysis of Tepezza for the treatment of TED ( Thyroid Eye Disease) at the American Academy of Ophthalmology Annual Meeting (AAO 2021). Tepezza is the first and only medicine approved by the FDA for the treatment of TED – a serious, progressive and potentially vision-threatening rare autoimmune disease. The analysis found […]

Molecular link traced from gene to late-onset retinal degeneration

Clinical trial planning underway to test the widely used diabetes drug metformin as a preventive treatment for the blinding eye disease. Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease. Researchers from the National Eye Institute (NEI), part of the National Institutes of Health […]