Evidence-based recommendations on menopause management advise individualized care

Best practice recommendations for healthcare professionals providing help and support to women experiencing the menopause have been issued in a joint position statement from the British Menopause Society (BMS), Royal College of Obstetricians and Gynaecologists (RCOG) and the Society for Endocrinology (SfE). The statement is in response to growing concerns around hormone replacement therapy (HRT) shortages and provides an expert […]

Obesity-related fertility issues may be improved by correcting blood sugar levels

Reproductive hormone levels in females with obesity may be partially restored by lowering blood glucose levels, leading to improved fertility, according to a study published in the Journal of Endocrinology. The study indicates that altered levels of reproductive hormones in a well-established mouse model of obesity may be partially restored by a common type 2 diabetes medication that reduces blood glucose […]

Sodium valproate – the risks for pregnant women

A recent newspaper article drew attention to the increased risks of birth defects in children of mothers who have taken sodium valproate during pregnancy. IMI spoke to experienced mental health pharmacists, Yogita Dawda and Anshu Rayan to find out more about the risks and what can be done to raise awareness and minimise risks. As deputy chief pharmacist at Central […]

Permanent birth control methods for women have up to six percent failure rates

Hysteroscopic sterilization, a nonincisional procedure, was found to be as effective as minimally invasive laparoscopic sterilization in preventing pregnancy, but both methods had higher than expected failure rates, according to a new study led by an investigator at Weill Cornell Medicine. The comparative study, published April 12 in Fertility and Sterility, found that both methods had failure rates of five to […]

Sleep apnea may lead to increased joint pain in postmenopausal women

The menopause transition is associated with several health issues. The incidence of both sleep apnea and joint pain, for example, are higher in postmenopausal women. A new study aimed to investigate the association between various physical and psychological symptoms common during the menopause transition with sleep apnea. Study results are published online today in Menopause, the journal of The North American […]

Antibiotics after birth affects gut microbes of babies

Treating babies with antibiotics in the first week of life is linked with a decrease in healthy bacteria necessary amongst others to digest milk and an increase in antimicrobial resistance, research suggests. Experts say that clinicians should consider using antibiotics in a way that causes least harm to the newborns microbiome — the community of microbes that live in our […]

European Commission approves Lenvima + Keytruda to treat endometrial carcinoma – Eisai + Merck Inc.

Eisai Co., Ltd. and Merck Inc., announced that the European Commission has approved the combination of Lenvima, the orally available multiple receptor tyrosine kinase inhibitor discovered by Eisai, plus Keytruda, the anti-PD-1 therapy from Merck Inc., for the treatment of advanced or recurrent endometrial carcinoma in adults who have disease progression on or following prior treatment with a platinum-containing therapy […]

Phase III FURI study of ibrexafungerp shows positive clinical results in multiple fungal infections – Scynexis

Scynexis announced an oral presentation of analyses of interim data from its ongoing Phase III FURI study showing favorable clinical activity of oral Brexafemme (ibrexafungerp) in severe hospital-based fungal infections across multiple serious fungal infections. Data from an interim analysis of the combined data of 74 patients from the Phase III FURI clinical study evaluating oral ibrexafungerp for the treatment […]

Spicy breast milk?

Breast milk is the first food that babies consume. Various studies have suggested that the “taste experience” in early childhood influences eating behavior in adults. Unlike standardized infant formula, natural milk does not taste and smell the same every day. The differences are largely due to the maternal diet. No one-to-one transfer However, the taste and aroma of food consumed […]

Could umbilical cord stem cells cure blood cancer?

Stem cells have promised to be the catalyst for major strides in medical research for decades. While progress in some fields has been slower than initially hoped, scientists say advances in cell transplantation techniques are raising the prospect of curing patients with acute myeloid leukaemia (AML). In a new paper published in Leukemia, researchers from Osaka University compared two strategies […]