Simple blood test shows promise for screening common and dangerous pregnancy complications

Scientists at Ningbo University, China have identified biomarkers that could provide an early warning system for three common and dangerous pregnancy complications: pre-eclampsia, gestational diabetes, and a liver condition called intrahepatic cholestasis. All three conditions are dangerous; early diagnosis and treatment is key to preventing poor outcomes and lifelong consequences. Their causes are not fully understood, and nor is their […]

Drinking during pregnancy changes baby’s brain structure

A new MRI study reveals that consumption of alcohol, even in low to moderate amounts during pregnancy, can change the baby’s brain structure and delay brain development. Alcohol consumption during pregnancy can expose the foetus to a group of conditions called foetal alcohol spectrum disorders, increasing the risk of learning disabilities, behavioural problems or speech and language delays. ‘Unfortunately, many […]

Nifedipine effective for stabilizing blood pressure during induction of labor in women with preeclampsia

Pregnant women with severe preeclampsia taking a daily dose of blood pressure lowering nifedipine as labor is induced have achieved better blood pressure control during labor and were less likely to require fast-acting treatments to lower very high blood pressure. Researchers reported these findings on October 3, 2022 in Hypertension. “We know that bringing down very high blood pressure to […]

Pain is no joke in labor, but withdrawing laughing gas has no ill effects

Birthing women denied nitrous oxide (‘laughing gas’) to relieve labour pain during the COVID-19 pandemic have turned to opioids instead, without any adverse outcomes for mother or child, according to a new study by Australian clinicians. The study, at Lyell McEwin Hospital in Adelaide, looked at the impact of withholding nitrous oxide (N20), a decision adopted by numerous hospitals worldwide in the […]

Inflammatory bowel disease increases risks for pregnant women

Pregnant women with inflammatory bowel disease (IBD) and their babies face increased risks and complications compared to pregnant women without IBD. Those are the findings from a new University of Missouri School of Medicine study that examined outcomes of more than 8 million pregnancies. IBD is a term used for Crohn’s disease and ulcerative colitis, which are characterized by chronic […]

Positive results from phase III PRIME study of Zejula at Society of Gynecologic Oncology Meeting – Zai Lab + GSK

Zai Lab Limited presented data from the Phase III PRIME study of Zejula (niraparib) as maintenance therapy at the Society of Gynecologic Oncology annual meeting . Zejula demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS) with a tolerable safety profile in Chinese patients with newly diagnosed advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer (collectively […]

Evidence-based recommendations on menopause management advise individualized care

Best practice recommendations for healthcare professionals providing help and support to women experiencing the menopause have been issued in a joint position statement from the British Menopause Society (BMS), Royal College of Obstetricians and Gynaecologists (RCOG) and the Society for Endocrinology (SfE). The statement is in response to growing concerns around hormone replacement therapy (HRT) shortages and provides an expert […]

Obesity-related fertility issues may be improved by correcting blood sugar levels

Reproductive hormone levels in females with obesity may be partially restored by lowering blood glucose levels, leading to improved fertility, according to a study published in the Journal of Endocrinology. The study indicates that altered levels of reproductive hormones in a well-established mouse model of obesity may be partially restored by a common type 2 diabetes medication that reduces blood glucose […]

Sodium valproate – the risks for pregnant women

A recent newspaper article drew attention to the increased risks of birth defects in children of mothers who have taken sodium valproate during pregnancy. IMI spoke to experienced mental health pharmacists, Yogita Dawda and Anshu Rayan to find out more about the risks and what can be done to raise awareness and minimise risks. As deputy chief pharmacist at Central […]

Permanent birth control methods for women have up to six percent failure rates

Hysteroscopic sterilization, a nonincisional procedure, was found to be as effective as minimally invasive laparoscopic sterilization in preventing pregnancy, but both methods had higher than expected failure rates, according to a new study led by an investigator at Weill Cornell Medicine. The comparative study, published April 12 in Fertility and Sterility, found that both methods had failure rates of five to […]