New research may explain unexpected effects of common painkillers

Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin are widely used to treat pain and inflammation. But even at similar doses, different NSAIDs can have unexpected and unexplained effects on many diseases, including heart disease and cancer. Now, a new Yale-led study has uncovered a previously unknown process by which some NSAIDs affect the body. The finding may explain […]

After outpatient surgery, NSAIDs top codeine for pain control with less side-effects

When prescribed following outpatient surgery, nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen provide better pain control with less side-effects than the opioid codeine. Researchers reported these findings on June 14, 2021 in CMAJ/Canadian Medical Association Journal. “In all surgery types, subgroups and outcome time points, NSAIDs were equal or superior to codeine for postoperative pain,” said investigator Matthew Choi, MD, Associate […]