Mirtazapine is ineffective, possibly dangerous, for agitation in dementia

Mirtazapine, an antidepressant often used to treat agitation in patients with dementia, is ineffective, researchers reported on Oct. 21, 2021 in The Lancet. And the investigators found a potentially higher mortality with use of mirtazapine. “Our results indicate that mirtazapine, given with normal clinical care, is not clinically effective compared with placebo for the treatment of clinically significant agitation in […]