October 14, 2023

Commonly prescribed hypertension drug, amlodipine, not actually dangerous

A new paper in the journal Function, published by Oxford Univetrsity Press, finds that a widely prescribed drug for treating hypertension, amlodipine, is not dangerous for patients, despite recent concerns from researchers and clinicians that taking amlodipine may have risks. Approximately 700,000 Americans die from hypertension each year and researchers believe some 116 million Americans (and one in five adults worldwide) have […]

admin Health 0 1 min read
June 19, 2023

Bayer starts phase II/III study with vericiguat in children with heart failure

Bayer and its development partner MSD (a tradename of Merck & Co., Inc., Rahway, NJ, USA) announced that the first patient has been enrolled in the Phase II/III VALOR trial. VALOR will investigate the efficacy, afety, and pharmacokinetics of vericiguat (Verquvo) in pediatric patients aged greater than 28 days to 18 years with heart failure due to left ventricular systolic […]

admin Health 0 1 min read
June 3, 2023

FDA approval for Inpefa to treat heart failure – Lexicon Pharma

Lexicon Pharmaceuticals, Inc. announced that the FDA has approved Inpefa (sotagliflozin), a once-daily oral tablet to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with: heart failure or type 2 diabetes mellitus, chronic kidney disease, and other cardiovascular risk factors. The broad label encompasses heart failure patients across the full range […]

admin Health 0 41 sec read
March 16, 2023

Hunger hormone could help patients with heart failure

The hunger hormone ghrelin appears to increase pumping capacity in patients with heart failure, researchers reported on March 14, 2023 in European Heart Journal. “Heart failure is the most common cause of hospitalisation in older generations and is associated with a poor quality of life and high mortality,” said investigator Lars Lund,  MD, Ph.D, Professor of Cardiology at Karolinska Institutet and Karolinska University Hospital […]

admin Health 0 1 min read
February 16, 2023

Donor hearts can be reprogrammed with medication for longer storage, improved transplant outcomes

Hundreds of thousands of Americans with heart failure are sick enough to benefit from a transplant, yet only around 4,000 heart transplants are performed annually. One reason for this gap is the time window during which a heart can survive outside the donor body before transplant hovers around four hours. And the longer it takes for the donor heart to […]

admin Health 0 4 min read
March 22, 2022

Pilot study suggests artificial intelligence could help assess, improve heart transplant outcomes

Heart transplantation can be a lifesaving operation for patients with end-stage heart failure. However, many patients experience organ transplant rejection, in which the immune system begins attacking the transplanted organ. But detecting transplant rejection is challenging — in its early stages, patients may not experience symptoms, and experts do not always agree on the degree and severity of the rejection. […]

admin Health 0 2 min read
February 1, 2022

EMPEROR-Preserved phase III trial of Jardiance shows efficacy in heart failure – Eli Lilly + Boehringer

Jardiance (empagliflozin), from Eli Lilly and Boehringer, reduced the risk for the composite primary endpoint of cardiovascular death or hospitalization for heart failure and slowed kidney function decline in adults with heart failure with left ventricular ejection fraction (LVEF) over 40% regardless of chronic kidney disease status at baseline, according to findings from a new prespecified sub-analysis of the EMPEROR-Preserved […]

admin Health 0 1 min read
June 30, 2021

Jardiance is EU approved for the treatment of heart failure with reduced ejection fraction – Boehringer + Eli Lilly

Copyright © ICR (UK) Limited t/a International Medical Information (IMI). Registered in the UK Company no. 05894351 medicalupdateonline.com is brought to you by International Medical Information. For more details, visit http://www.medicalimi.com Disclaimer: All information on this site has been collated by healthcare professionals from around the globe. Where every possible step has been taken to ensure its accuracy, MedicalUpdateOnline cannot […]

admin Health 0 27 sec read

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