A novel artificial intelligence blood testing technology developed and used by Johns Hopkins Kimmel Cancer Center researchers to successfully detect lung cancer in a 2021 study has now detected more than 80% of liver cancers in a new study of 724 people. The blood test, called DELFI (DNA evaluation of fragments for early interception) detects fragmentation changes among DNA from […]
Mount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the blood cancer multiple myeloma who try an immunotherapy known as CAR-T only to find their cancer coming back afterwards. CAR-T, short for chimeric antigen receptor T-cell therapy, enlists immune cells called T cells to fight multiple myeloma by altering them in […]
An epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by activating the immune system, reports a new Northwestern Medicine study done in mice. It’s the first time a drug used in hematologic malignancies and rare sarcomas has been used to treat one of the most common solid […]
Tenecteplase, a clot buster used off-label for treating ischemic stroke, outperforms alteplase, the standard treatment, in health outcomes and cost, researchers reported on September 23, 2022 in Stroke. Tenecteplase is administered in a single five- to 10-second intravenous injection. Alteplase is injected over a 60-minute period. “When it comes to treating patients with a stroke, every second matters,” said lead […]
Why do up to 80 per cent of patients with bone marrow cancer (multiple myeloma) develop bone damage (osteolysis) in some regions of the body while others are spared this damage? This is a question that has not yet been sufficiently investigated. On a research stay in Buffalo, New York, the senior physician PD Dr Maximilian Merz from Leipzig was […]
A research team led by Professor Moon In-kyu of the Department of Robotics and Mechatronics Engineering at DGIST (President Kuk Yang) developed an AI holography system that automatically extracts important information and inspects the quality of red blood cells. It is expected to become a key technology that enables cleaner and healthier red blood cell injections to patients through accurate […]
Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoporosis occurs when osteoclasts dominate without adequate bone formation to compensate. In new research published in the Journal of Bone and Mineral Research, elevated blood levels of a certain chemokine, or small signaling protein, that promotes osteoclast formation were linked with a higher risk […]
Although kidney transplantation is the most effective treatment for children with kidney failure, rejection of the transplanted organ by the recipient’s immune system is a major concern. Transplant recipients must take life-long immunosuppressant drugs, most commonly tacrolimus, and some patients experience large fluctuations in blood levels of tacrolimus even when the dose is unchanged—a phenomenon called high tacrolimus intrapatient variability. […]
People with hematologic malignancies—or blood cancers including leukemia, lymphoma, and multiple myeloma—have an impaired immune system due to their disease and its treatment, putting them at risk of severe COVID-19 infection and experiencing a reduced response to COVID-19 vaccination. In a recent study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, less than half of patients with […]
Global Blood Therapeutics announced the European Commission (EC) has granted Marketing Authorization for Oxbryta (voxelotor) for the treatment of hemolytic anemia due to sickle cell disease (SCD) in adult and pediatric patients 12 years of age and older as monotherapy or in combination with hydroxycarbamide (hydroxyurea). Oxbryta, a once-daily, oral treatment, is the first medicine approved in Europe that directly […]
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