When PrEP (pre-exposure prophylaxis), a drug that prevents HIV infection, was first approved by the FDA in 2012, it was a medical breakthrough that promised to drastically reduce HIV transmission. Traditionally, PrEP is administered via a pill that needs to be taken at the same time every day. Now, there are even more delivery options. A new UConn study explores […]
For the millions of people living with diabetes, insulin is a life-saving drug. Unlike many other medicines, though, insulin cannot be easily delivered by swallowing a pill — it needs to be injected under the skin with a syringe or pump. Researchers have been making steps toward an insulin pill, and now, a team reports in ACS Nano that they’ve delivered insulin […]
For many, inhalers are a sort of miracle drug. From gasping for air one minute, to breathing normally the next, patients can experience significant relief after one or two puffs. What few people realize is that these life-saving medicines can actually stop working in the long term, especially in people who use them often and in high doses. Researchers around […]
Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug’s key-in-a-lock fit with its target and the drug’s ability to make its way across the cellular membrane and get to that target in the first place. Now, a new study published […]
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