Number of dementia cases could be 42% higher than previously estimated by 2040

Up to 1.7 million people could be living with dementia in England and Wales by 2040 – over 40% more than previously forecast – finds a new UCL-led study. Previous studies, based on data up to 2010, showed that dementia incidence had declined in high-income countries. However, the new research, published in The Lancet Public Health, indicates that dementia incidence started […]

Are antipsychotic drugs being appropriately prescribed to homebound patients with dementia?

New research published in the Journal of the American Geriatrics Society indicates that antipsychotics are likely overprescribed and used inappropriately among patients with Alzheimer’s disease and related dementias (ADRD) receiving home health care, and such use is linked to worse patient outcomes. Antipsychotic drugs are not approved for the treatment of dementia—they are mostly used off-label to manage the symptoms that many […]

Is bone health linked to brain health?

People who have low bone density may have an increased risk of developing dementia compared to people who have higher bone density, according to a study published in the March 22, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that low bone density causes dementia. It only shows an association. “Low […]

One in 10 older Americans has dementia

In the first nationally representative study of cognitive impairment prevalence in more than 20 years, Columbia University researchers have found almost 10% of U.S. adults ages 65 and older have dementia, while another 22% have mild cognitive impairment. People with dementia and mild cognitive impairment are more likely to be older, have lower levels of education, and to be racialized […]

Older diabetes treatment appears to have anti-dementia effect

Researchers report a link between use of glitazones to treat type 2 diabetes and a 22% reduced risk of dementia. The findings appeared on Oct 11, 2022 in BMJ Open Diabetes Research & Care. “These findings may help inform medication selection for [older] patients with [type 2 diabetes] at high risk of dementia,” the authors said. As background, the authors noted […]

Mirtazapine is ineffective, possibly dangerous, for agitation in dementia

Mirtazapine, an antidepressant often used to treat agitation in patients with dementia, is ineffective, researchers reported on Oct. 21, 2021 in The Lancet. And the investigators found a potentially higher mortality with use of mirtazapine. “Our results indicate that mirtazapine, given with normal clinical care, is not clinically effective compared with placebo for the treatment of clinically significant agitation in […]

Menopausal hormone therapy not linked to dementia onset

Menopausal hormone therapy (MHT — also known as hormone replacement therapy, HRT) does not appear to increase the risk of dementia onset, researchers reported on Sept. 29, 2021 in the BMJ/British Medical Journal. “We are happy to be able to report findings that will reassure women needing menopausal hormone therapy and facilitate conversations between doctors and patients about the safest […]