Hospitals prevent deadly fungal infection during pandemic

As COVID-19 infections threatened to overwhelm hospitals in March 2020, infection control specialists worried not just about SARS-CoV-2 but also about other viral, bacterial and fungal diseases. C. auris is a type of fungus that causes severe, often fatal infections and is resistant to most antifungal drugs. It can be carried on a patient’s skin and can survive on surfaces for […]

EMA boost for COVID-19 vaccine production

The European Medicines Agency has approved additional manufacturing capacity for two companies producing vaccines against COVID-19. The news comes as European countries continue to roll out vaccines amid rising rates of the delta variant of the virus. The medicines watchdog, which has played a leading role in approving vaccines and inspecting manufacturing facilities, gave the green light to a site […]

Positive new data for Johnson & Johnson single-shot COVID-19 vaccine on activity against Delta variant and long-lasting durability of response

Johnson & Johnson announced data that demonstrated its single-shot COVID-19 vaccine generated strong, persistent activity against the rapidly spreading Delta variant and other highly prevalent SARS-CoV-2 viral variants. In addition, the data showed that the durability of the immune response lasted through at least eight months, the length of time evaluated to date. The two preprint study summaries have been […]

SARS-CoV-2 infection starts in nasal ciliated cells

Journal of Clinical Investigation The discovery that multiciliated cells in the nasal epithelium are the first cells to be targeted in early COVID-19 infection might provide the rationale for treatment using suitable antiviral nasal sprays. Led by Director KOH Gou Young, scientists from the Center for Vascular Research within the Institute for Basic Science, South Korea, have recently uncovered the […]

Liposomal ivermectin in cancer treatment

Interview and article by Christine Clark. The anti-tumour effects of ivermectin have been described in the literature and the liposomal delivery system developed by Mountain Valley MD could be the key to making this work in practice, according to Dennis Hancock, President and CEO of Mountain Valley MD. [embedded content] The anti-tumour effects of ivermectin have been reported in the […]

Liposomal drug delivery for ivermectin and vaccines

Interview and article by Christine Clark. Liposomal drug delivery holds out the prospect of oral drug administration without the need for water and vaccine more economical use of oral vaccines, according to Dennis Hancock, President and CEO of Mountain Valley MD. [embedded content] IvectosolTM, the solubilised form of ivermectin produced by Mountain Valley MD has been tested against three variants […]

Solubilised ivermectin improves drug delivery

Interview and article by Christine Clark. Patented solubilisation technology improves the bioavailability of oral ivermectin and makes possible the formulation of an ivermectin injection for human use, according to recent work undertaken by Mountain Valley MD in Canada.  IMI spoke to Dennis Hancock, President and CEO of Mountain Valley MD to find out more. [embedded content] Mountain Valley MD is […]

Metabolic hormone ‘leptin’ linked to poor vaccine response

Reduced levels of a metabolic hormone known as leptin is linked to poor vaccine antibody responses in the general population, a University of Queensland study has found. The researchers made the discovery while investigating several cohorts’ responses to the influenza vaccine or hepatitis B vaccine pre-COVID. UQ’s Professor Di Yu identified a link between the metabolic and immune systems that […]

Mild COVID-19 induces lasting antibody protection, study finds

People who have had mild illness develop antibody-producing cells that can last lifetime Washington University School of Medicine Months after recovering from mild cases of COVID-19, people still have immune cells in their body pumping out antibodies against the virus that causes COVID-19, according to a study from researchers at Washington University School of Medicine in St. Louis. Such cells […]

MHRA approves Ad26.COV2-S [recombinant] for active immunisation against COVID-19 within the United Kingdom – Janssen

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