Migraine: how to diagnose, manage and prevent

Migraine is a major cause of disability, affecting about 12% of people. A 2-part series published in CMAJ (Canadian Medical Association Journal) on diagnosing and managing the condition with both acute and preventive therapy provides guidance for clinicians https://www.cmaj.ca/lookup/doi/10.1503/cmaj.211969. “The goal of treatment of migraine attacks is to provide rapid relief from pain and other migraine-related symptoms, to restore patient function and […]

New study sheds light on why opioids can cause gastrointestinal problems

Opioids are the gold standard for treatment of chronic and acute pain; however, their use may result in significant gastrointestinal side effects, including nausea, vomiting, and constipation. The reasons behind these side effects are not well understood. A new study in The American Journal of Pathology, published by Elsevier, is the first report of how opioids like morphine cause gastric inflammation […]